Issues:
Sections:
Issue 98
GENERAL BIOLOGY
UDK: 582.894 (470.67)
SWIDA AUSTRALIS AS A POTENTIAL SOURCE OF SQUALENE
SULEIMANOVA Farida V.,
ISMAILOV Aziz B.
Nowadays, squalene is recognized for its diverse biological activities, including anti-cancer, antioxidant, detoxifying, and skin-moisturizing effects. It also acts as a protective agent, mitigating the side effects of chemotherapy and enhancing the immune response to various antigens. Given these properties, identifying novel sources of squalene is of significant relevance, with common dogwood oil representing a potential candidate. This study demonstrates a method for quantifying squalene using preparative high-performance liquid chromatography. This technique enables the simultaneous separation of complex mixtures and the isolation of high-purity compounds. After three purification passes, high-purity squalene was isolated. The yield of fatty oil extracted from S. australis seeds was 27.32%, with an initial squalene content of 9% relative to the total oil mass. A single pass through the chromatographic column increased the squalene concentration to 52.309% of the total sample.
Pages: 44 - 48
Date: 30.11.2025